NCOR2-ITGB5 Fusion FISH Probe
The NCOR2-ITGB5 Fusion FISH Probe is used to confirm a fusion of the NCOR2 and ITGB5 genes. The fusion of the NCOR2 and ITGB5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCOR2-ITGB5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-RERE | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-REOR | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-REGO | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-REGR | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-REAQ | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-ORRE | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-OROR | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-ORGO | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-GORE | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-GOOR | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-GOGO | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-GOGR | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-GRRE | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-GROR | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-GRGO | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-GRGR | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-AQRE | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-AQOR | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-AQGO | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-AQGR | 20 (40 μL) | 200 μL |
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| NCOR2-ITGB5-20-AQAQ | 20 (40 μL) | 200 μL |
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ITGB5 Gene Summary
This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017]
Gene Name: Integrin Subunit Beta 5
Chromosome: CHR3: 124481794 -124606144
Locus: 3q21.2
NCOR2 Gene Summary
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
Gene Name: Nuclear Receptor Corepressor 2
Chromosome: CHR12: 124808956 -125052010
Locus: 12q24.31
Gene Diseases
The NCOR2 ITGB5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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