NCOR2-NUP37 Fusion FISH Probe
The NCOR2-NUP37 Fusion FISH Probe is used to confirm a fusion of the NCOR2 and NUP37 genes. The fusion of the NCOR2 and NUP37 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCOR2-NUP37-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-RERE | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-REOR | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-REGO | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-REGR | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-REAQ | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-ORRE | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-OROR | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-ORGO | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-GORE | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-GOOR | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-GOGO | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-GOGR | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-GRRE | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-GROR | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-GRGO | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-GRGR | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-AQRE | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-AQOR | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-AQGO | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-AQGR | 20 (40 μL) | 200 μL |
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| NCOR2-NUP37-20-AQAQ | 20 (40 μL) | 200 μL |
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NCOR2 Gene Summary
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
Gene Name: Nuclear Receptor Corepressor 2
Chromosome: CHR12: 124808956 -125052010
Locus: 12q24.31
NUP37 Gene Summary
Nuclear pore complexes (NPCs) are used for transporting macromolecules between the cytoplasm and the nucleus. NPCs consist of multiple copies of 30 distinct proteins (nucleoporins), which assemble into biochemically-separable subcomplexes. The protein encoded by this gene is part of a subcomplex (Nup107-160) that is required for proper NPC function as well as for normal kinetochore-microtubule interaction and mitosis. [provided by RefSeq, Dec 2015]
Gene Name: Nucleoporin 37
Chromosome: CHR12: 102467972 -102512361
Locus: 12q23.2
Gene Diseases
The NCOR2 NUP37 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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