NDEL1-CHD3 Fusion FISH Probe
The NDEL1-CHD3 Fusion FISH Probe is used to confirm a fusion of the NDEL1 and CHD3 genes. The fusion of the NDEL1 and CHD3 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NDEL1-CHD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-RERE | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-REOR | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-REGO | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-REGR | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-REAQ | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-ORRE | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-OROR | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-ORGO | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-ORAQ | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-GORE | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-GOOR | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-GOGO | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-GOGR | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-GOAQ | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-GRRE | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-GROR | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-GRGO | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-GRGR | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-GRAQ | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-AQRE | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-AQOR | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-AQGO | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-AQGR | 20 (40 μL) | 200 μL |
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| NDEL1-CHD3-20-AQAQ | 20 (40 μL) | 200 μL |
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CHD3 Gene Summary
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Chromodomain Helicase DNA Binding Protein 3
Chromosome: CHR17: 7788122 -7816075
Locus: 17p13.1
NDEL1 Gene Summary
This gene encodes a coiled-coil protein that plays a role in multiple processes including cytoskeletal organization, cell signaling and neuron migration, outgrowth and maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Mar 2012]
Gene Name: NudE Neurodevelopment Protein 1 Like 1
Chromosome: CHR17: 8339178 -8371481
Locus: 17p13.1
Gene Diseases
The NDEL1 CHD3 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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