NDRG1-PLEKHA5 Fusion FISH Probe
The NDRG1-PLEKHA5 Fusion FISH Probe is used to confirm a fusion of the NDRG1 and PLEKHA5 genes. The fusion of the NDRG1 and PLEKHA5 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NDRG1-PLEKHA5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-RERE | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-REOR | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-REGO | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-REGR | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-REAQ | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-ORRE | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-OROR | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-ORGO | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-ORAQ | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-GORE | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-GOOR | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-GOGO | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-GOGR | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-GOAQ | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-GRRE | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-GROR | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-GRGO | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-GRGR | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-GRAQ | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-AQRE | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-AQOR | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-AQGO | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-AQGR | 20 (40 μL) | 200 μL |
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| NDRG1-PLEKHA5-20-AQAQ | 20 (40 μL) | 200 μL |
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NDRG1 Gene Summary
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Name: N-myc Downstream Regulated 1
Chromosome: CHR8: 134249413 -134309547
Locus: 8q24.22
PLEKHA5 Gene Summary
The Pleckstrin Homology Domain Containing A5 (PLEKHA5) gene is located on chr12 :19282625-19529333 at 12p12.3.
Gene Name: Pleckstrin Homology Domain Containing A5
Chromosome: CHR12: 19282625 -19529333
Locus: 12p12.3
Gene Diseases
The NDRG1 PLEKHA5 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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