SEARCH OUR PRODUCT CATALOG

NDRG2-SEC63 Fusion FISH Probe

The NDRG2-SEC63 Fusion FISH Probe is used to confirm a fusion of the NDRG2 and SEC63 genes. The fusion of the NDRG2 and SEC63 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NDRG2-SEC63-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
NDRG2-SEC63-20-RERE 20 (40 μL) 200 μL
NDRG2-SEC63-20-REOR 20 (40 μL) 200 μL
NDRG2-SEC63-20-REGO 20 (40 μL) 200 μL
NDRG2-SEC63-20-REGR 20 (40 μL) 200 μL
NDRG2-SEC63-20-REAQ 20 (40 μL) 200 μL
NDRG2-SEC63-20-ORRE 20 (40 μL) 200 μL
NDRG2-SEC63-20-OROR 20 (40 μL) 200 μL
NDRG2-SEC63-20-ORGO 20 (40 μL) 200 μL
NDRG2-SEC63-20-ORAQ 20 (40 μL) 200 μL
NDRG2-SEC63-20-GORE 20 (40 μL) 200 μL
NDRG2-SEC63-20-GOOR 20 (40 μL) 200 μL
NDRG2-SEC63-20-GOGO 20 (40 μL) 200 μL
NDRG2-SEC63-20-GOGR 20 (40 μL) 200 μL
NDRG2-SEC63-20-GOAQ 20 (40 μL) 200 μL
NDRG2-SEC63-20-GRRE 20 (40 μL) 200 μL
NDRG2-SEC63-20-GROR 20 (40 μL) 200 μL
NDRG2-SEC63-20-GRGO 20 (40 μL) 200 μL
NDRG2-SEC63-20-GRGR 20 (40 μL) 200 μL
NDRG2-SEC63-20-GRAQ 20 (40 μL) 200 μL
NDRG2-SEC63-20-AQRE 20 (40 μL) 200 μL
NDRG2-SEC63-20-AQOR 20 (40 μL) 200 μL
NDRG2-SEC63-20-AQGO 20 (40 μL) 200 μL
NDRG2-SEC63-20-AQGR 20 (40 μL) 200 μL
NDRG2-SEC63-20-AQAQ 20 (40 μL) 200 μL

SEC63 Gene Summary

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]

Gene Name: SEC63 Homolog, Protein Translocation Regulator

Chromosome: CHR6: 108188959 -108279482

Locus: 6q21

NDRG2 Gene Summary

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

Gene Name: NDRG Family Member 2

Chromosome: CHR14: 21484921 -21493935

Locus: 14q11.2

Gene Diseases

The NDRG2 SEC63 Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.