NDST1-TCOF1 Fusion FISH Probe
The NDST1-TCOF1 Fusion FISH Probe is used to confirm a fusion of the NDST1 and TCOF1 genes. The fusion of the NDST1 and TCOF1 genes has been associated with Lung Squamous Cell Carcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NDST1-TCOF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-RERE | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-REOR | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-REGO | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-REGR | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-REAQ | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-ORRE | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-OROR | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-ORGO | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-GORE | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-GOOR | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-GOGO | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-GOGR | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-GRRE | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-GROR | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-GRGO | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-GRGR | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-AQRE | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-AQOR | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-AQGO | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-AQGR | 20 (40 μL) | 200 μL |
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| NDST1-TCOF1-20-AQAQ | 20 (40 μL) | 200 μL |
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NDST1 Gene Summary
This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. The encoded protein catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to nitrogen of glucosamine in heparan sulfate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: N-deacetylase And N-sulfotransferase 1
Chromosome: CHR5: 149887673 -149937773
Locus: 5q33.1
TCOF1 Gene Summary
This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Name: Treacle Ribosome Biogenesis Factor 1
Chromosome: CHR5: 149737201 -149779871
Locus: 5q32-q33.1
Gene Diseases
The NDST1 TCOF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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