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NEDD1-PPFIA2 Fusion FISH Probe

The NEDD1-PPFIA2 Fusion FISH Probe is used to confirm a fusion of the NEDD1 and PPFIA2 genes. The fusion of the NEDD1 and PPFIA2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NEDD1-PPFIA2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-RERE 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-REOR 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-REGO 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-REGR 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-REAQ 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-ORRE 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-OROR 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-ORGO 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-ORAQ 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-GORE 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-GOOR 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-GOGO 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-GOGR 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-GOAQ 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-GRRE 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-GROR 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-GRGO 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-GRGR 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-GRAQ 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-AQRE 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-AQOR 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-AQGO 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-AQGR 20 (40 μL) 200 μL
NEDD1-PPFIA2-20-AQAQ 20 (40 μL) 200 μL

PPFIA2 Gene Summary

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Gene Name: PTPRF Interacting Protein Alpha 2

Chromosome: CHR12: 81652044 -82153109

Locus: 12q21.31

NEDD1 Gene Summary

The Neural Precursor Cell Expressed, Developmentally Down-regulated 1 (NEDD1) gene is located on chr12 :97301000-97347469 at 12q23.1.

Gene Name: Neural Precursor Cell Expressed, Developmentally Down-regulated 1

Chromosome: CHR12: 97301000 -97347469

Locus: 12q23.1

Gene Diseases

The NEDD1 PPFIA2 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.