NF1-EZH2 Fusion FISH Probe
The NF1-EZH2 Fusion FISH Probe is used to confirm a fusion of the NF1 and EZH2 genes. The fusion of the NF1 and EZH2 genes has been associated with Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NF1-EZH2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| NF1-EZH2-20-AQAQ | 20 (40 μL) | 200 μL |
|
EZH2 Gene Summary
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
Gene Name: Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit
Chromosome: CHR7: 148504463 -148581441
Locus: 7q36.1
NF1 Gene Summary
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Neurofibromin 1
Chromosome: CHR17: 29421944 -29704695
Locus: 17q11.2
Gene Diseases
The NF1 EZH2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|