NFASC-SOX13 Fusion FISH Probe
The NFASC-SOX13 Fusion FISH Probe is used to confirm a fusion of the NFASC and SOX13 genes. The fusion of the NFASC and SOX13 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFASC-SOX13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-RERE | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-REOR | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-REGO | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-REGR | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-REAQ | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-ORRE | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-OROR | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-ORGO | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-GORE | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-GOOR | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-GOGO | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-GOGR | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-GRRE | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-GROR | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-GRGO | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-GRGR | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-AQRE | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-AQOR | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-AQGO | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-AQGR | 20 (40 μL) | 200 μL |
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| NFASC-SOX13-20-AQAQ | 20 (40 μL) | 200 μL |
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SOX13 Gene Summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. [provided by RefSeq, Jul 2008]
Gene Name: SRY-box 13
Chromosome: CHR1: 204042245 -204096871
Locus: 1q32.1
NFASC Gene Summary
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009]
Gene Name: Neurofascin
Chromosome: CHR1: 204797781 -204991950
Locus: 1q32.1
Gene Diseases
The NFASC SOX13 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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