NFAT5-CRYM Fusion FISH Probe
The NFAT5-CRYM Fusion FISH Probe is used to confirm a fusion of the NFAT5 and CRYM genes. The fusion of the NFAT5 and CRYM genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFAT5-CRYM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-RERE | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-REOR | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-REGO | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-REGR | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-REAQ | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-ORRE | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-OROR | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-ORGO | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-GORE | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-GOOR | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-GOGO | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-GOGR | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-GRRE | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-GROR | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-GRGO | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-GRGR | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-AQRE | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-AQOR | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-AQGO | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-AQGR | 20 (40 μL) | 200 μL |
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| NFAT5-CRYM-20-AQAQ | 20 (40 μL) | 200 μL |
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CRYM Gene Summary
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. [provided by RefSeq, Sep 2014]
Gene Name: Crystallin Mu
Chromosome: CHR16: 21269838 -21314404
Locus: 16p12.2
NFAT5 Gene Summary
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Factor Of Activated T-cells 5
Chromosome: CHR16: 69599868 -69738569
Locus: 16q22.1
Gene Diseases
The NFAT5 CRYM Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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