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NFIC-CELF5 Fusion FISH Probe

The NFIC-CELF5 Fusion FISH Probe is used to confirm a fusion of the NFIC and CELF5 genes. The fusion of the NFIC and CELF5 genes has been associated with Liver Hepatocellular Carcinoma, Liver Hepatocellular Carcinoma, Brain Lower Grade Glioma, Brain Lower Grade Glioma, Bladder Urothelial Carcinoma, and Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NFIC-CELF5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
NFIC-CELF5-20-RERE 20 (40 μL) 200 μL
NFIC-CELF5-20-REOR 20 (40 μL) 200 μL
NFIC-CELF5-20-REGO 20 (40 μL) 200 μL
NFIC-CELF5-20-REGR 20 (40 μL) 200 μL
NFIC-CELF5-20-REAQ 20 (40 μL) 200 μL
NFIC-CELF5-20-ORRE 20 (40 μL) 200 μL
NFIC-CELF5-20-OROR 20 (40 μL) 200 μL
NFIC-CELF5-20-ORGO 20 (40 μL) 200 μL
NFIC-CELF5-20-ORAQ 20 (40 μL) 200 μL
NFIC-CELF5-20-GORE 20 (40 μL) 200 μL
NFIC-CELF5-20-GOOR 20 (40 μL) 200 μL
NFIC-CELF5-20-GOGO 20 (40 μL) 200 μL
NFIC-CELF5-20-GOGR 20 (40 μL) 200 μL
NFIC-CELF5-20-GOAQ 20 (40 μL) 200 μL
NFIC-CELF5-20-GRRE 20 (40 μL) 200 μL
NFIC-CELF5-20-GROR 20 (40 μL) 200 μL
NFIC-CELF5-20-GRGO 20 (40 μL) 200 μL
NFIC-CELF5-20-GRGR 20 (40 μL) 200 μL
NFIC-CELF5-20-GRAQ 20 (40 μL) 200 μL
NFIC-CELF5-20-AQRE 20 (40 μL) 200 μL
NFIC-CELF5-20-AQOR 20 (40 μL) 200 μL
NFIC-CELF5-20-AQGO 20 (40 μL) 200 μL
NFIC-CELF5-20-AQGR 20 (40 μL) 200 μL
NFIC-CELF5-20-AQAQ 20 (40 μL) 200 μL

NFIC Gene Summary

The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Gene Name: Nuclear Factor I C

Chromosome: CHR19: 3359615 -3463603

Locus: 19p13.3

CELF5 Gene Summary

This gene encodes a member of the the CELF/BRUNOL protein family, which contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing and translation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Gene Name: CUGBP Elav-like Family Member 5

Chromosome: CHR19: 3224700 -3297073

Locus: 19p13.3

Gene Diseases

The NFIC CELF5 Fusion has been associated with the following diseases:

Disease Name
Liver Hepatocellular Carcinoma
Liver Hepatocellular Carcinoma
Brain Lower Grade Glioma
Brain Lower Grade Glioma
Bladder Urothelial Carcinoma
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.