NFIX-CAPN12 Fusion FISH Probe
The NFIX-CAPN12 Fusion FISH Probe is used to confirm a fusion of the NFIX and CAPN12 genes. The fusion of the NFIX and CAPN12 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFIX-CAPN12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-RERE | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-REOR | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-REGO | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-REGR | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-REAQ | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-ORRE | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-OROR | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-ORGO | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-GORE | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-GOOR | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-GOGO | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-GOGR | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-GRRE | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-GROR | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-GRGO | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-GRGR | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-AQRE | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-AQOR | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-AQGO | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-AQGR | 20 (40 μL) | 200 μL |
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| NFIX-CAPN12-20-AQAQ | 20 (40 μL) | 200 μL |
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NFIX Gene Summary
The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
Gene Name: Nuclear Factor I X
Chromosome: CHR19: 13106583 -13209610
Locus: 19p13.13
CAPN12 Gene Summary
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012]
Gene Name: Calpain 12
Chromosome: CHR19: 39220831 -39235114
Locus: 19q13.2
Gene Diseases
The NFIX CAPN12 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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