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NFIX-DOCK6 Fusion FISH Probe

The NFIX-DOCK6 Fusion FISH Probe is used to confirm a fusion of the NFIX and DOCK6 genes. The fusion of the NFIX and DOCK6 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NFIX-DOCK6-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
NFIX-DOCK6-20-RERE 20 (40 μL) 200 μL
NFIX-DOCK6-20-REOR 20 (40 μL) 200 μL
NFIX-DOCK6-20-REGO 20 (40 μL) 200 μL
NFIX-DOCK6-20-REGR 20 (40 μL) 200 μL
NFIX-DOCK6-20-REAQ 20 (40 μL) 200 μL
NFIX-DOCK6-20-ORRE 20 (40 μL) 200 μL
NFIX-DOCK6-20-OROR 20 (40 μL) 200 μL
NFIX-DOCK6-20-ORGO 20 (40 μL) 200 μL
NFIX-DOCK6-20-ORAQ 20 (40 μL) 200 μL
NFIX-DOCK6-20-GORE 20 (40 μL) 200 μL
NFIX-DOCK6-20-GOOR 20 (40 μL) 200 μL
NFIX-DOCK6-20-GOGO 20 (40 μL) 200 μL
NFIX-DOCK6-20-GOGR 20 (40 μL) 200 μL
NFIX-DOCK6-20-GOAQ 20 (40 μL) 200 μL
NFIX-DOCK6-20-GRRE 20 (40 μL) 200 μL
NFIX-DOCK6-20-GROR 20 (40 μL) 200 μL
NFIX-DOCK6-20-GRGO 20 (40 μL) 200 μL
NFIX-DOCK6-20-GRGR 20 (40 μL) 200 μL
NFIX-DOCK6-20-GRAQ 20 (40 μL) 200 μL
NFIX-DOCK6-20-AQRE 20 (40 μL) 200 μL
NFIX-DOCK6-20-AQOR 20 (40 μL) 200 μL
NFIX-DOCK6-20-AQGO 20 (40 μL) 200 μL
NFIX-DOCK6-20-AQGR 20 (40 μL) 200 μL
NFIX-DOCK6-20-AQAQ 20 (40 μL) 200 μL

NFIX Gene Summary

The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]

Gene Name: Nuclear Factor I X

Chromosome: CHR19: 13106583 -13209610

Locus: 19p13.13

DOCK6 Gene Summary

This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2. [provided by RefSeq, Dec 2011]

Gene Name: Dedicator Of Cytokinesis 6

Chromosome: CHR19: 11309970 -11373157

Locus: 19p13.2

Gene Diseases

The NFIX DOCK6 Fusion has been associated with the following diseases:

Disease Name
Esophageal Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.