NFX1-C9ORF24 Fusion FISH Probe
The NFX1-C9ORF24 Fusion FISH Probe is used to confirm a fusion of the NFX1 and C9ORF24 genes. The fusion of the NFX1 and C9ORF24 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NFX1-C9ORF24-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-RERE | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-REOR | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-REGO | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-REGR | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-REAQ | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-ORRE | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-OROR | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-ORGO | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-ORAQ | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-GORE | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-GOOR | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-GOGO | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-GOGR | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-GOAQ | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-GRRE | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-GROR | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-GRGO | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-GRGR | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-GRAQ | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-AQRE | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-AQOR | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-AQGO | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-AQGR | 20 (40 μL) | 200 μL |
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| NFX1-C9ORF24-20-AQAQ | 20 (40 μL) | 200 μL |
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NFX1 Gene Summary
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Transcription Factor, X-box Binding 1
Chromosome: CHR9: 33290417 -33371155
Locus: 9p13.3
C9orf24 Gene Summary
This gene encodes a nuclear- or perinuclear-localized protein with no predicted domains or similarity to other known proteins. Expression of this gene is induced during the differentiation of bronchial epithelial cells, and the encoded protein may play a role in ciliogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Chromosome 9 Open Reading Frame 24
Chromosome: CHR9: 34379016 -34397849
Locus: 9p13.3
Gene Diseases
The NFX1 C9ORF24 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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