NFYA-AKT2 Fusion FISH Probe
The NFYA-AKT2 Fusion FISH Probe is used to confirm a fusion of the NFYA and AKT2 genes. The fusion of the NFYA and AKT2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NFYA-AKT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| NFYA-AKT2-20-AQAQ | 20 (40 μL) | 200 μL |
|
AKT2 Gene Summary
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]
Gene Name: AKT Serine/threonine Kinase 2
Chromosome: CHR19: 40736223 -40791302
Locus: 19q13.2
NFYA Gene Summary
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Transcription Factor Y Subunit Alpha
Chromosome: CHR6: 41040706 -41070146
Locus: 6p21.1
Gene Diseases
The NFYA AKT2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|