NHS-F11R Fusion FISH Probe
The NHS-F11R Fusion FISH Probe is used to confirm a fusion of the NHS and F11R genes. The fusion of the NHS and F11R genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NHS-F11R-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-RERE | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-REOR | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-REGR | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-OROR | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| NHS-F11R-20-AQAQ | 20 (40 μL) | 200 μL |
|
NHS Gene Summary
This gene encodes a protein containing four conserved nuclear localization signals. The encoded protein functions in eye, tooth, craniofacial and brain development, and it can regulate actin remodeling and cell morphology. Mutations in this gene have been shown to cause Nance-Horan syndrome, and also X-linked cataract-40. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2014]
Gene Name: NHS Actin Remodeling Regulator
Chromosome: CHRX: 17393542 -17754113
Locus: Xp22.2-p22.13
F11R Gene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
Gene Name: F11 Receptor
Chromosome: CHR1: 160965000 -160991133
Locus: 1q23.3
Gene Diseases
The NHS F11R Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|