NIN-STXBP6 Fusion FISH Probe
The NIN-STXBP6 Fusion FISH Probe is used to confirm a fusion of the NIN and STXBP6 genes. The fusion of the NIN and STXBP6 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NIN-STXBP6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-RERE | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-REOR | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-REGO | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-REGR | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-REAQ | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-ORRE | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-OROR | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-ORGO | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-ORAQ | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-GORE | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-GOOR | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-GOGO | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-GOGR | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-GOAQ | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-GRRE | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-GROR | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-GRGO | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-GRGR | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-GRAQ | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-AQRE | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-AQOR | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-AQGO | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-AQGR | 20 (40 μL) | 200 μL |
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| NIN-STXBP6-20-AQAQ | 20 (40 μL) | 200 μL |
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STXBP6 Gene Summary
STXBP6 binds components of the SNARE complex (see MIM 603215) and may be involved in regulating SNARE complex formation (Scales et al., 2002 [PubMed 12145319]).[supplied by OMIM, Mar 2008]
Gene Name: Syntaxin Binding Protein 6
Chromosome: CHR14: 25281305 -25519095
Locus: 14q12
NIN Gene Summary
This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Ninein
Chromosome: CHR14: 51186480 -51297839
Locus: 14q22.1
Gene Diseases
The NIN STXBP6 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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