NLGN4X-DMD Fusion FISH Probe
The NLGN4X-DMD Fusion FISH Probe is used to confirm a fusion of the NLGN4X and DMD genes. The fusion of the NLGN4X and DMD genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NLGN4X-DMD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-RERE | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-REOR | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-REGR | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-OROR | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| NLGN4X-DMD-20-AQAQ | 20 (40 μL) | 200 μL |
|
DMD Gene Summary
This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
Gene Name: Dystrophin
Chromosome: CHRX: 31137344 -33357726
Locus: Xp21.2-p21.1
NLGN4X Gene Summary
This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Name: Neuroligin 4, X-linked
Chromosome: CHRX: 5808082 -6146706
Locus: Xp22.32-p22.31
Gene Diseases
The NLGN4X DMD Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|