NLK-DOK5 Fusion FISH Probe
The NLK-DOK5 Fusion FISH Probe is used to confirm a fusion of the NLK and DOK5 genes. The fusion of the NLK and DOK5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NLK-DOK5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-RERE | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-REOR | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-REGR | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-OROR | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| NLK-DOK5-20-AQAQ | 20 (40 μL) | 200 μL |
|
NLK Gene Summary
The Nemo Like Kinase (NLK) gene is located on chr17 :26369687-26523404 at 17q11.2.
Gene Name: Nemo Like Kinase
Chromosome: CHR17: 26369687 -26523404
Locus: 17q11.2
DOK5 Gene Summary
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Name: Docking Protein 5
Chromosome: CHR20: 53092265 -53267710
Locus: 20q13.2
Gene Diseases
The NLK DOK5 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|