NLK-NF1 Fusion FISH Probe
The NLK-NF1 Fusion FISH Probe is used to confirm a fusion of the NLK and NF1 genes. The fusion of the NLK and NF1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NLK-NF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-RERE | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-REOR | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-REGO | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-REGR | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-REAQ | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-ORRE | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-OROR | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-ORGO | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-GORE | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-GOOR | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-GOGO | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-GOGR | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-GRRE | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-GROR | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-GRGO | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-GRGR | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-AQRE | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-AQOR | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-AQGO | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-AQGR | 20 (40 μL) | 200 μL |
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| NLK-NF1-20-AQAQ | 20 (40 μL) | 200 μL |
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NF1 Gene Summary
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Neurofibromin 1
Chromosome: CHR17: 29421944 -29704695
Locus: 17q11.2
NLK Gene Summary
The Nemo Like Kinase (NLK) gene is located on chr17 :26369687-26523404 at 17q11.2.
Gene Name: Nemo Like Kinase
Chromosome: CHR17: 26369687 -26523404
Locus: 17q11.2
Gene Diseases
The NLK NF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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