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NME7-MKLN1 Fusion FISH Probe

The NME7-MKLN1 Fusion FISH Probe is used to confirm a fusion of the NME7 and MKLN1 genes. The fusion of the NME7 and MKLN1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NME7-MKLN1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
NME7-MKLN1-20-RERE 20 (40 μL) 200 μL
NME7-MKLN1-20-REOR 20 (40 μL) 200 μL
NME7-MKLN1-20-REGO 20 (40 μL) 200 μL
NME7-MKLN1-20-REGR 20 (40 μL) 200 μL
NME7-MKLN1-20-REAQ 20 (40 μL) 200 μL
NME7-MKLN1-20-ORRE 20 (40 μL) 200 μL
NME7-MKLN1-20-OROR 20 (40 μL) 200 μL
NME7-MKLN1-20-ORGO 20 (40 μL) 200 μL
NME7-MKLN1-20-ORAQ 20 (40 μL) 200 μL
NME7-MKLN1-20-GORE 20 (40 μL) 200 μL
NME7-MKLN1-20-GOOR 20 (40 μL) 200 μL
NME7-MKLN1-20-GOGO 20 (40 μL) 200 μL
NME7-MKLN1-20-GOGR 20 (40 μL) 200 μL
NME7-MKLN1-20-GOAQ 20 (40 μL) 200 μL
NME7-MKLN1-20-GRRE 20 (40 μL) 200 μL
NME7-MKLN1-20-GROR 20 (40 μL) 200 μL
NME7-MKLN1-20-GRGO 20 (40 μL) 200 μL
NME7-MKLN1-20-GRGR 20 (40 μL) 200 μL
NME7-MKLN1-20-GRAQ 20 (40 μL) 200 μL
NME7-MKLN1-20-AQRE 20 (40 μL) 200 μL
NME7-MKLN1-20-AQOR 20 (40 μL) 200 μL
NME7-MKLN1-20-AQGO 20 (40 μL) 200 μL
NME7-MKLN1-20-AQGR 20 (40 μL) 200 μL
NME7-MKLN1-20-AQAQ 20 (40 μL) 200 μL

MKLN1 Gene Summary

Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]

Gene Name: Muskelin 1

Chromosome: CHR7: 130794854 -131181398

Locus: 7q32.3

NME7 Gene Summary

This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

Gene Name: NME/NM23 Family Member 7

Chromosome: CHR1: 169101768 -169337186

Locus: 1q24.2

Gene Diseases

The NME7 MKLN1 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.