NMT1-NME1-NME2 Fusion FISH Probe
The NMT1-NME1-NME2 Fusion FISH Probe is used to confirm a fusion of the NMT1 and NME1-NME2 genes. The fusion of the NMT1 and NME1-NME2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NMT1-NME1-NME2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-RERE | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-REOR | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-REGO | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-REGR | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-REAQ | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-ORRE | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-OROR | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-ORGO | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-GORE | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-GOOR | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-GOGO | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-GOGR | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-GRRE | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-GROR | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-GRGO | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-GRGR | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-AQRE | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-AQOR | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-AQGO | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-AQGR | 20 (40 μL) | 200 μL |
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| NMT1-NME1-NME2-20-AQAQ | 20 (40 μL) | 200 μL |
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NMT1 Gene Summary
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008]
Gene Name: N-myristoyltransferase 1
Chromosome: CHR17: 43138679 -43186382
Locus: 17q21.31
NME1-NME2 Gene Summary
This locus represents naturally occurring read-through transcription between the neighboring NME1 and NME2 genes. The significance of this read-through transcription and the function of the resulting protein product have not yet been determined. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Gene Name: NME1-NME2 Readthrough
Chromosome: CHR17: 49230896 -49249105
Locus: 17q21.33
Gene Diseases
The NMT1 NME1-NME2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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