NOL11-CARD11 Fusion FISH Probe
The NOL11-CARD11 Fusion FISH Probe is used to confirm a fusion of the NOL11 and CARD11 genes. The fusion of the NOL11 and CARD11 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NOL11-CARD11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-RERE | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-REOR | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-REGO | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-REGR | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-REAQ | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-ORRE | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-OROR | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-ORGO | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-ORAQ | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-GORE | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-GOOR | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-GOGO | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-GOGR | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-GOAQ | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-GRRE | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-GROR | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-GRGO | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-GRGR | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-GRAQ | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-AQRE | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-AQOR | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-AQGO | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-AQGR | 20 (40 μL) | 200 μL |
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| NOL11-CARD11-20-AQAQ | 20 (40 μL) | 200 μL |
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NOL11 Gene Summary
The Nucleolar Protein 11 (NOL11) gene is located on chr17 :65714060-65740266 at 17q24.2.
Gene Name: Nucleolar Protein 11
Chromosome: CHR17: 65714060 -65740266
Locus: 17q24.2
CARD11 Gene Summary
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
Gene Name: Caspase Recruitment Domain Family Member 11
Chromosome: CHR7: 2945709 -3083509
Locus: 7p22.2
Gene Diseases
The NOL11 CARD11 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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