NOL8-FXN Fusion FISH Probe
The NOL8-FXN Fusion FISH Probe is used to confirm a fusion of the NOL8 and FXN genes. The fusion of the NOL8 and FXN genes has been associated with Testicular Germ Cell Tumors. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NOL8-FXN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-RERE | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-REOR | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-REGO | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-REGR | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-REAQ | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-ORRE | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-OROR | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-ORGO | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-ORAQ | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-GORE | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-GOOR | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-GOGO | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-GOGR | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-GOAQ | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-GRRE | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-GROR | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-GRGO | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-GRGR | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-GRAQ | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-AQRE | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-AQOR | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-AQGO | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-AQGR | 20 (40 μL) | 200 μL |
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| NOL8-FXN-20-AQAQ | 20 (40 μL) | 200 μL |
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FXN Gene Summary
This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Gene Name: Frataxin
Chromosome: CHR9: 71650478 -71715094
Locus: 9q21.11
NOL8 Gene Summary
NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth (Sekiguchi et al., 2004 [PubMed 14660641]).[supplied by OMIM, Mar 2008]
Gene Name: Nucleolar Protein 8
Chromosome: CHR9: 95059639 -95087876
Locus: 9q22.31
Gene Diseases
The NOL8 FXN Fusion has been associated with the following diseases:
| Disease Name |
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| Testicular Germ Cell Tumors |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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