NR2C2-FGD5 Fusion FISH Probe
The NR2C2-FGD5 Fusion FISH Probe is used to confirm a fusion of the NR2C2 and FGD5 genes. The fusion of the NR2C2 and FGD5 genes has been associated with Thymoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NR2C2-FGD5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-RERE | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-REOR | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-REGO | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-REGR | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-REAQ | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-ORRE | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-OROR | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-ORGO | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-ORAQ | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-GORE | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-GOOR | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-GOGO | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-GOGR | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-GOAQ | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-GRRE | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-GROR | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-GRGO | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-GRGR | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-GRAQ | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-AQRE | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-AQOR | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-AQGO | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-AQGR | 20 (40 μL) | 200 μL |
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| NR2C2-FGD5-20-AQAQ | 20 (40 μL) | 200 μL |
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NR2C2 Gene Summary
This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Gene Name: Nuclear Receptor Subfamily 2 Group C Member 2
Chromosome: CHR3: 14989235 -15090780
Locus: 3p25.1
FGD5 Gene Summary
The FYVE, RhoGEF And PH Domain Containing 5 (FGD5) gene is located on chr3 :14860468-14976072 at 3p25.1.
Gene Name: FYVE, RhoGEF And PH Domain Containing 5
Chromosome: CHR3: 14860468 -14976072
Locus: 3p25.1
Gene Diseases
The NR2C2 FGD5 Fusion has been associated with the following diseases:
| Disease Name |
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| Thymoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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