NRG1-STMN2 Fusion FISH Probe
The NRG1-STMN2 Fusion FISH Probe is used to confirm a fusion of the NRG1 and STMN2 genes. The fusion of the NRG1 and STMN2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NRG1-STMN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-RERE | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-REOR | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-REGO | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-REGR | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-REAQ | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-ORRE | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-OROR | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-ORGO | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-GORE | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-GOOR | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-GOGO | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-GOGR | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-GRRE | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-GROR | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-GRGO | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-GRGR | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-AQRE | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-AQOR | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-AQGO | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-AQGR | 20 (40 μL) | 200 μL |
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| NRG1-STMN2-20-AQAQ | 20 (40 μL) | 200 μL |
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NRG1 Gene Summary
The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]
Gene Name: Neuregulin 1
Chromosome: CHR8: 31497267 -32600770
Locus: 8p12
STMN2 Gene Summary
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010]
Gene Name: Stathmin 2
Chromosome: CHR8: 80523048 -80578410
Locus: 8q21.13
Gene Diseases
The NRG1 STMN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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