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NSMAF-LETM2 Fusion FISH Probe

The NSMAF-LETM2 Fusion FISH Probe is used to confirm a fusion of the NSMAF and LETM2 genes. The fusion of the NSMAF and LETM2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NSMAF-LETM2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
NSMAF-LETM2-20-RERE 20 (40 μL) 200 μL
NSMAF-LETM2-20-REOR 20 (40 μL) 200 μL
NSMAF-LETM2-20-REGO 20 (40 μL) 200 μL
NSMAF-LETM2-20-REGR 20 (40 μL) 200 μL
NSMAF-LETM2-20-REAQ 20 (40 μL) 200 μL
NSMAF-LETM2-20-ORRE 20 (40 μL) 200 μL
NSMAF-LETM2-20-OROR 20 (40 μL) 200 μL
NSMAF-LETM2-20-ORGO 20 (40 μL) 200 μL
NSMAF-LETM2-20-ORAQ 20 (40 μL) 200 μL
NSMAF-LETM2-20-GORE 20 (40 μL) 200 μL
NSMAF-LETM2-20-GOOR 20 (40 μL) 200 μL
NSMAF-LETM2-20-GOGO 20 (40 μL) 200 μL
NSMAF-LETM2-20-GOGR 20 (40 μL) 200 μL
NSMAF-LETM2-20-GOAQ 20 (40 μL) 200 μL
NSMAF-LETM2-20-GRRE 20 (40 μL) 200 μL
NSMAF-LETM2-20-GROR 20 (40 μL) 200 μL
NSMAF-LETM2-20-GRGO 20 (40 μL) 200 μL
NSMAF-LETM2-20-GRGR 20 (40 μL) 200 μL
NSMAF-LETM2-20-GRAQ 20 (40 μL) 200 μL
NSMAF-LETM2-20-AQRE 20 (40 μL) 200 μL
NSMAF-LETM2-20-AQOR 20 (40 μL) 200 μL
NSMAF-LETM2-20-AQGO 20 (40 μL) 200 μL
NSMAF-LETM2-20-AQGR 20 (40 μL) 200 μL
NSMAF-LETM2-20-AQAQ 20 (40 μL) 200 μL

NSMAF Gene Summary

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]

Gene Name: Neutral Sphingomyelinase Activation Associated Factor

Chromosome: CHR8: 59496063 -59572404

Locus: 8q12.1

LETM2 Gene Summary

The Leucine Zipper And EF-hand Containing Transmembrane Protein 2 (LETM2) gene is located on chr8 :38243958-38266062 at 8p11.23.

Gene Name: Leucine Zipper And EF-hand Containing Transmembrane Protein 2

Chromosome: CHR8: 38243958 -38266062

Locus: 8p11.23

Gene Diseases

The NSMAF LETM2 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.