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NSMCE2-WDR67 Fusion FISH Probe

The NSMCE2-WDR67 Fusion FISH Probe is used to confirm a fusion of the NSMCE2 and WDR67 genes. The fusion of the NSMCE2 and WDR67 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NSMCE2-WDR67-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
NSMCE2-WDR67-20-RERE 20 (40 μL) 200 μL
NSMCE2-WDR67-20-REOR 20 (40 μL) 200 μL
NSMCE2-WDR67-20-REGO 20 (40 μL) 200 μL
NSMCE2-WDR67-20-REGR 20 (40 μL) 200 μL
NSMCE2-WDR67-20-REAQ 20 (40 μL) 200 μL
NSMCE2-WDR67-20-ORRE 20 (40 μL) 200 μL
NSMCE2-WDR67-20-OROR 20 (40 μL) 200 μL
NSMCE2-WDR67-20-ORGO 20 (40 μL) 200 μL
NSMCE2-WDR67-20-ORAQ 20 (40 μL) 200 μL
NSMCE2-WDR67-20-GORE 20 (40 μL) 200 μL
NSMCE2-WDR67-20-GOOR 20 (40 μL) 200 μL
NSMCE2-WDR67-20-GOGO 20 (40 μL) 200 μL
NSMCE2-WDR67-20-GOGR 20 (40 μL) 200 μL
NSMCE2-WDR67-20-GOAQ 20 (40 μL) 200 μL
NSMCE2-WDR67-20-GRRE 20 (40 μL) 200 μL
NSMCE2-WDR67-20-GROR 20 (40 μL) 200 μL
NSMCE2-WDR67-20-GRGO 20 (40 μL) 200 μL
NSMCE2-WDR67-20-GRGR 20 (40 μL) 200 μL
NSMCE2-WDR67-20-GRAQ 20 (40 μL) 200 μL
NSMCE2-WDR67-20-AQRE 20 (40 μL) 200 μL
NSMCE2-WDR67-20-AQOR 20 (40 μL) 200 μL
NSMCE2-WDR67-20-AQGO 20 (40 μL) 200 μL
NSMCE2-WDR67-20-AQGR 20 (40 μL) 200 μL
NSMCE2-WDR67-20-AQAQ 20 (40 μL) 200 μL

NSMCE2 Gene Summary

This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017]

Gene Name: NSE2/MMS21 Homolog, SMC5-SMC6 Complex SUMO Ligase

Chromosome: CHR8: 126104082 -126379367

Locus: 8q24.13

Gene Diseases

The NSMCE2 WDR67 Fusion has been associated with the following diseases:

Disease Name
Pancreatic Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.