NSUN4-BMPR1B Fusion FISH Probe
The NSUN4-BMPR1B Fusion FISH Probe is used to confirm a fusion of the NSUN4 and BMPR1B genes. The fusion of the NSUN4 and BMPR1B genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NSUN4-BMPR1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-RERE | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-REOR | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-REGO | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-REGR | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-REAQ | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-ORRE | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-OROR | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-ORGO | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-GORE | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-GOOR | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-GOGO | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-GOGR | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-GRRE | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-GROR | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-GRGO | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-GRGR | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-AQRE | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-AQOR | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-AQGO | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-AQGR | 20 (40 μL) | 200 μL |
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| NSUN4-BMPR1B-20-AQAQ | 20 (40 μL) | 200 μL |
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BMPR1B Gene Summary
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Gene Name: Bone Morphogenetic Protein Receptor Type 1B
Chromosome: CHR4: 95679127 -96079601
Locus: 4q22.3
NSUN4 Gene Summary
The NOP2/Sun RNA Methyltransferase Family Member 4 (NSUN4) gene is located on chr1 :46806389-46830690 at 1p33.
Gene Name: NOP2/Sun RNA Methyltransferase Family Member 4
Chromosome: CHR1: 46806389 -46830690
Locus: 1p33
Gene Diseases
The NSUN4 BMPR1B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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