NUDT2-UBAP1 Fusion FISH Probe
The NUDT2-UBAP1 Fusion FISH Probe is used to confirm a fusion of the NUDT2 and UBAP1 genes. The fusion of the NUDT2 and UBAP1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUDT2-UBAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-RERE | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-REOR | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-REGO | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-REGR | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-OROR | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-GORE | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-GROR | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| NUDT2-UBAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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NUDT2 Gene Summary
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]
Gene Name: Nudix Hydrolase 2
Chromosome: CHR9: 34329503 -34343711
Locus: 9p13.3
UBAP1 Gene Summary
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Name: Ubiquitin Associated Protein 1
Chromosome: CHR9: 34179002 -34252521
Locus: 9p13.3
Gene Diseases
The NUDT2 UBAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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