NUMA1-FOLR1 Fusion FISH Probe
The NUMA1-FOLR1 Fusion FISH Probe is used to confirm a fusion of the NUMA1 and FOLR1 genes. The fusion of the NUMA1 and FOLR1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUMA1-FOLR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-RERE | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-REOR | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-REGO | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-REGR | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-REAQ | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-ORRE | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-OROR | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-ORGO | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-GORE | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-GOOR | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-GOGO | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-GOGR | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-GRRE | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-GROR | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-GRGO | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-GRGR | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-AQRE | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-AQOR | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-AQGO | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-AQGR | 20 (40 μL) | 200 μL |
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| NUMA1-FOLR1-20-AQAQ | 20 (40 μL) | 200 μL |
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FOLR1 Gene Summary
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Name: Folate Receptor 1
Chromosome: CHR11: 71900601 -71907367
Locus: 11q13.4
NUMA1 Gene Summary
This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Name: Nuclear Mitotic Apparatus Protein 1
Chromosome: CHR11: 71713910 -71791573
Locus: 11q13.4
Gene Diseases
The NUMA1 FOLR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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