NUP153-NEDD9 Fusion FISH Probe
The NUP153-NEDD9 Fusion FISH Probe is used to confirm a fusion of the NUP153 and NEDD9 genes. The fusion of the NUP153 and NEDD9 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUP153-NEDD9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-RERE | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-REOR | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-REGO | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-REGR | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-REAQ | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-ORRE | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-OROR | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-ORGO | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-GORE | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-GOOR | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-GOGO | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-GOGR | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-GRRE | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-GROR | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-GRGO | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-GRGR | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-AQRE | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-AQOR | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-AQGO | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-AQGR | 20 (40 μL) | 200 μL |
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| NUP153-NEDD9-20-AQAQ | 20 (40 μL) | 200 μL |
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NEDD9 Gene Summary
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Name: Neural Precursor Cell Expressed, Developmentally Down-regulated 9
Chromosome: CHR6: 11183530 -11382581
Locus: 6p24.2
NUP153 Gene Summary
Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Gene Name: Nucleoporin 153
Chromosome: CHR6: 17615268 -17706818
Locus: 6p22.3
Gene Diseases
The NUP153 NEDD9 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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