NXT2-COL4A5 Fusion FISH Probe
The NXT2-COL4A5 Fusion FISH Probe is used to confirm a fusion of the NXT2 and COL4A5 genes. The fusion of the NXT2 and COL4A5 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NXT2-COL4A5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-RERE | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-REOR | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-REGO | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-REGR | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-REAQ | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-ORRE | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-OROR | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-ORGO | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-ORAQ | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-GORE | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-GOOR | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-GOGO | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-GOGR | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-GOAQ | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-GRRE | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-GROR | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-GRGO | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-GRGR | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-GRAQ | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-AQRE | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-AQOR | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-AQGO | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-AQGR | 20 (40 μL) | 200 μL |
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| NXT2-COL4A5-20-AQAQ | 20 (40 μL) | 200 μL |
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COL4A5 Gene Summary
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
Gene Name: Collagen Type IV Alpha 5 Chain
Chromosome: CHRX: 107683153 -107940775
Locus: Xq22.3
NXT2 Gene Summary
The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011]
Gene Name: Nuclear Transport Factor 2 Like Export Factor 2
Chromosome: CHRX: 108779009 -108787927
Locus: Xq23
Gene Diseases
The NXT2 COL4A5 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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