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OSBPL1A-RIOK3 Fusion FISH Probe

The OSBPL1A-RIOK3 Fusion FISH Probe is used to confirm a fusion of the OSBPL1A and RIOK3 genes. The fusion of the OSBPL1A and RIOK3 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
OSBPL1A-RIOK3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-RERE 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-REOR 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-REGO 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-REGR 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-REAQ 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-ORRE 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-OROR 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-ORGO 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-ORAQ 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-GORE 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-GOOR 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-GOGO 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-GOGR 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-GOAQ 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-GRRE 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-GROR 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-GRGO 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-GRGR 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-GRAQ 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-AQRE 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-AQOR 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-AQGO 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-AQGR 20 (40 μL) 200 μL
OSBPL1A-RIOK3-20-AQAQ 20 (40 μL) 200 μL

RIOK3 Gene Summary

This gene was first identified by the similarity of its product to the Aspergillus nidulans SUDD protein. This gene is now recognized as a member of the right open reading frame (RIO) kinase gene family. This gene encodes a serine/threonine kinase that localizes to the cytoplasm and plays a role in the processing of the pre-40 S ribosomal subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017]

Gene Name: RIO Kinase 3

Chromosome: CHR18: 21032786 -21063099

Locus: 18q11.2

OSBPL1A Gene Summary

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008]

Gene Name: Oxysterol Binding Protein Like 1A

Chromosome: CHR18: 21742010 -21977833

Locus: 18q11.2

Gene Diseases

The OSBPL1A RIOK3 Fusion has been associated with the following diseases:

Disease Name
Head And Neck Squamous Cell Carcinoma 

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.