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OSBPL9-FKBP5 Fusion FISH Probe

The OSBPL9-FKBP5 Fusion FISH Probe is used to confirm a fusion of the OSBPL9 and FKBP5 genes. The fusion of the OSBPL9 and FKBP5 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
OSBPL9-FKBP5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-RERE 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-REOR 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-REGO 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-REGR 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-REAQ 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-ORRE 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-OROR 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-ORGO 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-ORAQ 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-GORE 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-GOOR 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-GOGO 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-GOGR 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-GOAQ 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-GRRE 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-GROR 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-GRGO 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-GRGR 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-GRAQ 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-AQRE 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-AQOR 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-AQGO 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-AQGR 20 (40 μL) 200 μL
OSBPL9-FKBP5-20-AQAQ 20 (40 μL) 200 μL

FKBP5 Gene Summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

Gene Name: FK506 Binding Protein 5

Chromosome: CHR6: 35541361 -35696360

Locus: 6p21.31

OSBPL9 Gene Summary

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010]

Gene Name: Oxysterol Binding Protein Like 9

Chromosome: CHR1: 52082545 -52254891

Locus: 1p32.3

Gene Diseases

The OSBPL9 FKBP5 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.