PARP4-COL9A1 Fusion FISH Probe
The PARP4-COL9A1 Fusion FISH Probe is used to confirm a fusion of the PARP4 and COL9A1 genes. The fusion of the PARP4 and COL9A1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PARP4-COL9A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-RERE | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-REOR | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-REGO | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-REGR | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-REAQ | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-ORRE | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-OROR | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-ORGO | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-GORE | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-GOOR | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-GOGO | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-GOGR | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-GRRE | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-GROR | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-GRGO | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-GRGR | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-AQRE | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-AQOR | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-AQGO | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-AQGR | 20 (40 μL) | 200 μL |
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| PARP4-COL9A1-20-AQAQ | 20 (40 μL) | 200 μL |
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PARP4 Gene Summary
This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]
Gene Name: Poly(ADP-ribose) Polymerase Family Member 4
Chromosome: CHR13: 24995068 -25086948
Locus: 13q12.12
COL9A1 Gene Summary
This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Collagen Type IX Alpha 1 Chain
Chromosome: CHR6: 70925742 -71012786
Locus: 6q13
Gene Diseases
The PARP4 COL9A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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