PARP4-GDF1 Fusion FISH Probe
The PARP4-GDF1 Fusion FISH Probe is used to confirm a fusion of the PARP4 and GDF1 genes. The fusion of the PARP4 and GDF1 genes has been associated with Thymoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PARP4-GDF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-RERE | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-REOR | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-REGO | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-REGR | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-REAQ | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-ORRE | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-OROR | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-ORGO | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-GORE | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-GOOR | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-GOGO | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-GOGR | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-GRRE | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-GROR | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-GRGO | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-GRGR | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-AQRE | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-AQOR | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-AQGO | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-AQGR | 20 (40 μL) | 200 μL |
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| PARP4-GDF1-20-AQAQ | 20 (40 μL) | 200 μL |
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PARP4 Gene Summary
This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]
Gene Name: Poly(ADP-ribose) Polymerase Family Member 4
Chromosome: CHR13: 24995068 -25086948
Locus: 13q12.12
GDF1 Gene Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Jul 2016]
Gene Name: Growth Differentiation Factor 1
Chromosome: CHR19: 18979360 -19006953
Locus: 19p13.11
Gene Diseases
The PARP4 GDF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Thymoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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