PARVB-SAMM50 Fusion FISH Probe
The PARVB-SAMM50 Fusion FISH Probe is used to confirm a fusion of the PARVB and SAMM50 genes. The fusion of the PARVB and SAMM50 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PARVB-SAMM50-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-RERE | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-REOR | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-REGO | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-REGR | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-REAQ | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-ORRE | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-OROR | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-ORGO | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-ORAQ | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-GORE | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-GOOR | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-GOGO | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-GOGR | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-GOAQ | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-GRRE | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-GROR | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-GRGO | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-GRGR | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-GRAQ | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-AQRE | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-AQOR | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-AQGO | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-AQGR | 20 (40 μL) | 200 μL |
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| PARVB-SAMM50-20-AQAQ | 20 (40 μL) | 200 μL |
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SAMM50 Gene Summary
This gene encodes a component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The Sam complex functions in the assembly of beta-barrel proteins into the outer mitochondrial membrane.[provided by RefSeq, Jun 2011]
Gene Name: SAMM50 Sorting And Assembly Machinery Component
Chromosome: CHR22: 44351260 -44392412
Locus: 22q13.31
PARVB Gene Summary
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Name: Parvin Beta
Chromosome: CHR22: 44395090 -44565112
Locus: 22q13.31
Gene Diseases
The PARVB SAMM50 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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