PAWR-MOSC1 Fusion FISH Probe
The PAWR-MOSC1 Fusion FISH Probe is used to confirm a fusion of the PAWR and MOSC1 genes. The fusion of the PAWR and MOSC1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAWR-MOSC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PAWR-MOSC1-20-AQAQ | 20 (40 μL) | 200 μL |
|
PAWR Gene Summary
This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases. [provided by RefSeq, Aug 2017]
Gene Name: Pro-apoptotic WT1 Regulator
Chromosome: CHR12: 79985744 -80084790
Locus: 12q21.2
Gene Diseases
The PAWR MOSC1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|