PBXIP1-GBAP1 Fusion FISH Probe
The PBXIP1-GBAP1 Fusion FISH Probe is used to confirm a fusion of the PBXIP1 and GBAP1 genes. The fusion of the PBXIP1 and GBAP1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PBXIP1-GBAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-RERE | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-REOR | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-REGO | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-REGR | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-OROR | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-GORE | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-GROR | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| PBXIP1-GBAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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GBAP1 Gene Summary
The Glucosylceramidase Beta Pseudogene 1 (GBAP1) gene is located on chr1 :155183615-155197325 at 1q22.
Gene Name: Glucosylceramidase Beta Pseudogene 1
Chromosome: CHR1: 155183615 -155197325
Locus: 1q22
PBXIP1 Gene Summary
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined. [provided by RefSeq, Dec 2015]
Gene Name: PBX Homeobox Interacting Protein 1
Chromosome: CHR1: 154916558 -154928567
Locus: 1q21.3
Gene Diseases
The PBXIP1 GBAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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