PCCA-CLYBL Fusion FISH Probe
The PCCA-CLYBL Fusion FISH Probe is used to confirm a fusion of the PCCA and CLYBL genes. The fusion of the PCCA and CLYBL genes has been associated with Breast Invasive Carcinoma, Liver Hepatocellular Carcinoma, Bladder Urothelial Carcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PCCA-CLYBL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-RERE | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-REOR | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-REGO | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-REGR | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-REAQ | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-ORRE | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-OROR | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-ORGO | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-ORAQ | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-GORE | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-GOOR | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-GOGO | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-GOGR | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-GOAQ | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-GRRE | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-GROR | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-GRGO | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-GRGR | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-GRAQ | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-AQRE | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-AQOR | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-AQGO | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-AQGR | 20 (40 μL) | 200 μL |
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| PCCA-CLYBL-20-AQAQ | 20 (40 μL) | 200 μL |
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PCCA Gene Summary
The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
Gene Name: Propionyl-CoA Carboxylase Alpha Subunit
Chromosome: CHR13: 100741268 -101182691
Locus: 13q32.3
CLYBL Gene Summary
The Citrate Lyase Beta Like (CLYBL) gene is located on chr13 :100258918-100549388 at 13q32.3.
Gene Name: Citrate Lyase Beta Like
Chromosome: CHR13: 100258918 -100549388
Locus: 13q32.3
Gene Diseases
The PCCA CLYBL Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Liver Hepatocellular Carcinoma |
| Bladder Urothelial Carcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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