PCID2-ATP4B Fusion FISH Probe
The PCID2-ATP4B Fusion FISH Probe is used to confirm a fusion of the PCID2 and ATP4B genes. The fusion of the PCID2 and ATP4B genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PCID2-ATP4B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-RERE | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-REOR | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-REGO | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-REGR | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-REAQ | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-ORRE | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-OROR | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-ORGO | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-GORE | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-GOOR | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-GOGO | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-GOGR | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-GRRE | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-GROR | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-GRGO | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-GRGR | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-AQRE | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-AQOR | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-AQGO | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-AQGR | 20 (40 μL) | 200 μL |
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| PCID2-ATP4B-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP4B Gene Summary
The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]
Gene Name: ATPase H+/K+ Transporting Beta Subunit
Chromosome: CHR13: 114303121 -114312513
Locus: 13q34
PCID2 Gene Summary
This gene encodes a component of the TREX-2 complex (transcription and export complex 2), which regulates mRNA export from the nucleus. This protein regulates expression of Mad2 mitotic arrest deficient-like 1, a cell division checkpoint protein. This protein also interacts with and stabilizes Brca2 (breast cancer 2) protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: PCI Domain Containing 2
Chromosome: CHR13: 113831924 -113863029
Locus: 13q34
Gene Diseases
The PCID2 ATP4B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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