PDCD6-FRS2 Fusion FISH Probe
The PDCD6-FRS2 Fusion FISH Probe is used to confirm a fusion of the PDCD6 and FRS2 genes. The fusion of the PDCD6 and FRS2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDCD6-FRS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-RERE | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-REOR | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-REGO | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-REGR | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-REAQ | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-ORRE | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-OROR | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-ORGO | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-GORE | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-GOOR | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-GOGO | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-GOGR | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-GRRE | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-GROR | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-GRGO | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-GRGR | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-AQRE | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-AQOR | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-AQGO | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-AQGR | 20 (40 μL) | 200 μL |
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| PDCD6-FRS2-20-AQAQ | 20 (40 μL) | 200 μL |
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PDCD6 Gene Summary
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012]
Gene Name: Programmed Cell Death 6
Chromosome: CHR5: 271735 -315089
Locus: 5p15.33
FRS2 Gene Summary
The Fibroblast Growth Factor Receptor Substrate 2 (FRS2) gene is located on chr12 :69864128-69973562 at 12q15.
Gene Name: Fibroblast Growth Factor Receptor Substrate 2
Chromosome: CHR12: 69864128 -69973562
Locus: 12q15
Gene Diseases
The PDCD6 FRS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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