PDDC1-ALOX5AP Fusion FISH Probe
The PDDC1-ALOX5AP Fusion FISH Probe is used to confirm a fusion of the PDDC1 and ALOX5AP genes. The fusion of the PDDC1 and ALOX5AP genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDDC1-ALOX5AP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-RERE | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-REOR | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-REGO | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-REGR | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-REAQ | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-ORRE | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-OROR | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-ORGO | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-GORE | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-GOOR | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-GOGO | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-GOGR | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-GRRE | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-GROR | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-GRGO | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-GRGR | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-AQRE | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-AQOR | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-AQGO | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-AQGR | 20 (40 μL) | 200 μL |
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| PDDC1-ALOX5AP-20-AQAQ | 20 (40 μL) | 200 μL |
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ALOX5AP Gene Summary
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
Gene Name: Arachidonate 5-lipoxygenase Activating Protein
Chromosome: CHR13: 31287614 -31338565
Locus: 13q12.3
Gene Diseases
The PDDC1 ALOX5AP Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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