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PDE4D-RFWD2 Fusion FISH Probe

The PDE4D-RFWD2 Fusion FISH Probe is used to confirm a fusion of the PDE4D and RFWD2 genes. The fusion of the PDE4D and RFWD2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PDE4D-RFWD2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PDE4D-RFWD2-20-RERE 20 (40 μL) 200 μL
PDE4D-RFWD2-20-REOR 20 (40 μL) 200 μL
PDE4D-RFWD2-20-REGO 20 (40 μL) 200 μL
PDE4D-RFWD2-20-REGR 20 (40 μL) 200 μL
PDE4D-RFWD2-20-REAQ 20 (40 μL) 200 μL
PDE4D-RFWD2-20-ORRE 20 (40 μL) 200 μL
PDE4D-RFWD2-20-OROR 20 (40 μL) 200 μL
PDE4D-RFWD2-20-ORGO 20 (40 μL) 200 μL
PDE4D-RFWD2-20-ORAQ 20 (40 μL) 200 μL
PDE4D-RFWD2-20-GORE 20 (40 μL) 200 μL
PDE4D-RFWD2-20-GOOR 20 (40 μL) 200 μL
PDE4D-RFWD2-20-GOGO 20 (40 μL) 200 μL
PDE4D-RFWD2-20-GOGR 20 (40 μL) 200 μL
PDE4D-RFWD2-20-GOAQ 20 (40 μL) 200 μL
PDE4D-RFWD2-20-GRRE 20 (40 μL) 200 μL
PDE4D-RFWD2-20-GROR 20 (40 μL) 200 μL
PDE4D-RFWD2-20-GRGO 20 (40 μL) 200 μL
PDE4D-RFWD2-20-GRGR 20 (40 μL) 200 μL
PDE4D-RFWD2-20-GRAQ 20 (40 μL) 200 μL
PDE4D-RFWD2-20-AQRE 20 (40 μL) 200 μL
PDE4D-RFWD2-20-AQOR 20 (40 μL) 200 μL
PDE4D-RFWD2-20-AQGO 20 (40 μL) 200 μL
PDE4D-RFWD2-20-AQGR 20 (40 μL) 200 μL
PDE4D-RFWD2-20-AQAQ 20 (40 μL) 200 μL

PDE4D Gene Summary

This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]

Gene Name: Phosphodiesterase 4D

Chromosome: CHR5: 58264865 -59783925

Locus: 5q11.2-q12.1

RFWD2 Gene Summary

The Ring Finger And WD Repeat Domain 2 (RFWD2) gene is located on chr1 :175913966-176176370 at 1q25.1-q25.2.

Gene Name: Ring Finger And WD Repeat Domain 2

Chromosome: CHR1: 175913966 -176176370

Locus: 1q25.1-q25.2

Gene Diseases

The PDE4D RFWD2 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.