PDE7B-KIF21A Fusion FISH Probe
The PDE7B-KIF21A Fusion FISH Probe is used to confirm a fusion of the PDE7B and KIF21A genes. The fusion of the PDE7B and KIF21A genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDE7B-KIF21A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-RERE | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-REOR | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-REGO | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-REGR | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-REAQ | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-ORRE | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-OROR | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-ORGO | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-GORE | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-GOOR | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-GOGO | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-GOGR | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-GRRE | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-GROR | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-GRGO | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-GRGR | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-AQRE | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-AQOR | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-AQGO | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-AQGR | 20 (40 μL) | 200 μL |
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| PDE7B-KIF21A-20-AQAQ | 20 (40 μL) | 200 μL |
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PDE7B Gene Summary
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.[provided by RefSeq, Apr 2009]
Gene Name: Phosphodiesterase 7B
Chromosome: CHR6: 136172833 -136516709
Locus: 6q23.3
KIF21A Gene Summary
This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]
Gene Name: Kinesin Family Member 21A
Chromosome: CHR12: 39687029 -39837192
Locus: 12q12
Gene Diseases
The PDE7B KIF21A Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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