PDLIM3-ZFYVE28 Fusion FISH Probe
The PDLIM3-ZFYVE28 Fusion FISH Probe is used to confirm a fusion of the PDLIM3 and ZFYVE28 genes. The fusion of the PDLIM3 and ZFYVE28 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDLIM3-ZFYVE28-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-RERE | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-REOR | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-REGO | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-REGR | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-REAQ | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-ORRE | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-OROR | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-ORGO | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-GORE | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-GOOR | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-GOGO | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-GOGR | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-GRRE | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-GROR | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-GRGO | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-GRGR | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-AQRE | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-AQOR | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-AQGO | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-AQGR | 20 (40 μL) | 200 μL |
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| PDLIM3-ZFYVE28-20-AQAQ | 20 (40 μL) | 200 μL |
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PDLIM3 Gene Summary
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012]
Gene Name: PDZ And LIM Domain 3
Chromosome: CHR4: 186421814 -186456712
Locus: 4q35.1
ZFYVE28 Gene Summary
The Zinc Finger FYVE-type Containing 28 (ZFYVE28) gene is located on chr4 :2271323-2420370 at 4p16.3.
Gene Name: Zinc Finger FYVE-type Containing 28
Chromosome: CHR4: 2271323 -2420370
Locus: 4p16.3
Gene Diseases
The PDLIM3 ZFYVE28 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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