PDXDC1-MMP14 Fusion FISH Probe
The PDXDC1-MMP14 Fusion FISH Probe is used to confirm a fusion of the PDXDC1 and MMP14 genes. The fusion of the PDXDC1 and MMP14 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDXDC1-MMP14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-RERE | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-REOR | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-REGO | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-REGR | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-REAQ | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-ORRE | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-OROR | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-ORGO | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-GORE | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-GOOR | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-GOGO | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-GOGR | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-GRRE | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-GROR | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-GRGO | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-GRGR | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-AQRE | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-AQOR | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-AQGO | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-AQGR | 20 (40 μL) | 200 μL |
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| PDXDC1-MMP14-20-AQAQ | 20 (40 μL) | 200 μL |
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MMP14 Gene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
Gene Name: Matrix Metallopeptidase 14
Chromosome: CHR14: 23305792 -23316803
Locus: 14q11.2
PDXDC1 Gene Summary
The Pyridoxal Dependent Decarboxylase Domain Containing 1 (PDXDC1) gene is located on chr16 :15068832-15131552 at 16p13.11.
Gene Name: Pyridoxal Dependent Decarboxylase Domain Containing 1
Chromosome: CHR16: 15068832 -15131552
Locus: 16p13.11
Gene Diseases
The PDXDC1 MMP14 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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