PDZRN3-CACNA2D3 Fusion FISH Probe
The PDZRN3-CACNA2D3 Fusion FISH Probe is used to confirm a fusion of the PDZRN3 and CACNA2D3 genes. The fusion of the PDZRN3 and CACNA2D3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PDZRN3-CACNA2D3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-RERE | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-REOR | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-REGO | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-REGR | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-REAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-ORRE | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-OROR | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-ORGO | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-GORE | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-GOOR | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-GOGO | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-GOGR | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-GRRE | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-GROR | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-GRGO | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-GRGR | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-AQRE | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-AQOR | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-AQGO | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-AQGR | 20 (40 μL) | 200 μL |
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| PDZRN3-CACNA2D3-20-AQAQ | 20 (40 μL) | 200 μL |
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PDZRN3 Gene Summary
This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Name: PDZ Domain Containing Ring Finger 3
Chromosome: CHR3: 73431651 -73674072
Locus: 3p13
CACNA2D3 Gene Summary
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Gene Name: Calcium Voltage-gated Channel Auxiliary Subunit Alpha2delta 3
Chromosome: CHR3: 54156692 -55108584
Locus: 3p21.1-p14.3
Gene Diseases
The PDZRN3 CACNA2D3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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