PFKP-CAMK2G Fusion FISH Probe
The PFKP-CAMK2G Fusion FISH Probe is used to confirm a fusion of the PFKP and CAMK2G genes. The fusion of the PFKP and CAMK2G genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PFKP-CAMK2G-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-RERE | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-REOR | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-REGO | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-REGR | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-REAQ | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-ORRE | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-OROR | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-ORGO | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-ORAQ | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-GORE | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-GOOR | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-GOGO | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-GOGR | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-GOAQ | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-GRRE | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-GROR | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-GRGO | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-GRGR | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-GRAQ | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-AQRE | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-AQOR | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-AQGO | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-AQGR | 20 (40 μL) | 200 μL |
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| PFKP-CAMK2G-20-AQAQ | 20 (40 μL) | 200 μL |
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CAMK2G Gene Summary
The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011]
Gene Name: Calcium/calmodulin Dependent Protein Kinase II Gamma
Chromosome: CHR10: 75572258 -75634349
Locus: 10q22.2
PFKP Gene Summary
This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Gene Name: Phosphofructokinase, Platelet
Chromosome: CHR10: 3109711 -3178997
Locus: 10p15.2
Gene Diseases
The PFKP CAMK2G Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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